Winners ECNP Excellence Awards 2022

P.0011
Predilection for addiction: is cocaine addiction in your genes’ back pocket?
Graczyk Michal Mateusz, United Kingdom

P.0019
Hevin protein is altered in postmortem brain of alcoholic subjects and in ethanol treated mice’s brain and plasma
Nuñez-delMoral Amaia, Spain

P.0042
Social adolescent stress causes increased general anxiety in male rats and reduced social anxiety in both male and female rats
Manojlović Marina, Serbia

P.0047
Whole transcriptome expression analysis of long terminal repeat elements in children with autism spectrum disorder
Minchev Danail, Bulgaria

P.0051
Moving towards a reliable multimodal predictive model of clinical outcomes in anorexia nervosa
Derissen Mara, Germany

P.0053
Temporal changes of visual attention to high-calorie foods in adolescents with anorexia nervosa: An eye-tracking study
Akcay Elif, Türkiye

P.0079
DNA base excision repair genes in unipolar and bipolar depression
Yılmaz Selda, Türkiye

P.0082
Abelson helper integration site 1 haplotypes and peripheral blood expression associates with lithium response in bipolar patients
Sakrajda Kosma, Poland

P.0083
Functional polymorphism of CLDN5 has stress mediating effect on current depressive symptoms
Gál Zsófia, Hungary

P.0084
The relationship between cognitive functions, childhood traumas and microRNAs associated with major depressive disorder
Mert Alper, Türkiye

P.0091
A machine learning pipeline for efficient differentiation between depressed bipolar disorder and major depressive disorder patients based on structural neuroimaging
Calesella Federico, Italy

P.0093
Predicting antidepressant treatment outcome in major depressive disorder using multi-domain data: A NeuroPharm study
Dam Vibeke Høyrup, Denmark

P.0101
Resting-state fronto-limbic connectivity in unipolar depressive patients as a predictor for sporadic conversion to (hypo)mania
Tajioui Ikrame, The Netherlands

P.0105
Characterizing the course of gray matter volume change from one week to 6 months after electroconvulsive therapy in depressed patients
Laroy Maarten, Belgium

P.0114
CYP2C19 slow metabolizer phenotype is associated with lower antidepressant efficacy and tolerability: clinical study on 102 inpatients
Milosavljević Filip, Serbia

P.0133
Humanized CYP2C19 transgenic mouse as an animal model of cerebellar ataxia
Atanasov Andrea, Serbia

P.0139
Altered CNS–immune system crosstalk and its link to disease severity in multiple sclerosis
Brasanac Jelena, Germany

P.0140
Exosomes obtained from amyloid-beta toxicity applied cells induce Alzheimer's disease-like pathology in the brain of C57BL/6 mice
Kalkan Çakmak Rabia, Türkiye

P.0143
Ghrelin receptor agonist MK-0677 alleviates motor impairments caused by spreading alpha-synuclein aggregation in bilaterally alpha-synuclein fibrils injected mice
Maziarz Katarzyna, Poland

P.0171
A volumetric paradox – Larger basal ganglia in medication-naive first episode psychosis
Yesilkaya Umit Haluk, Türkiye

P.0223
Alpha2-adrenergic receptor blockade in the ventral tegmental area interferes with acquisition but not retrieval of fear memories
Bernacka Joanna, Poland

P.0240
Is there any room for objective cognitive impairment in subjective cognitive decline?
Pavel Alexandru, Romania

P.0244
Effects of single orally administrated different sized microplastic particles – acute toxicity study in adult male rats
Stojanović Zoran, Serbia

P.0252
Acute psilocybin and ketanserin effects on cerebral blood flow: 5-HT2AR neuromodulatory effects in healthy humans
Larsen Kristian, Denmark

P.0269
Investigation of the age-related role of exosomes in the exacerbation of amyloid beta pathology at the molecular level
Sarikamis Bahar, Türkiye

P.0270
Transgenic mice with progressive degeneration of noradrenergic neurons restricted to locus coeruleus present depressive-like behavior and motor disturbances
Rafa-Zablocka Katarzyna, Poland

P.0281
The impairment of expression of the important proteins in some brain areas in diabetes mellitus: the effect of nicotinamide
Tykhonenko Tetiana, Ukraine

P.0314
Concurrent antiepileptic and antipsychotic use moderates lithium’s effects on regional brain volumes: a mega-analysis from the ENIGMA-Bipolar Disorder Working Group
King Sinead, Ireland

P.0325
The early life microbiota-gut-brain-axis: the temporal relation between infant microbial development and subsequent childhood social-emotional development in healthy children
Bloemendaal Mirjam, The Netherlands

P.0330
Neurochemical properties of psilocybin in comparison to ketamine in vivo
Wojtas Adam, Poland

P.0332
Pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of oral psilocybin administration in healthy subjects
Holze Friederike, Switzerland

P.0333
Ketanserin reverses the acute effects of LSD in healthy subjects
Becker Anna M., Switzerland

P.0385
First presentation of Asperger’s syndrome in paediatric patients
Iotu Alexandra-Diana, Romania

P.0391
Topiramate treatment attenuates mood and cognitive disabilities in a model of temporal lobe epilepsy in rats
Shishmanova-Doseva Mihaela, Bulgaria

P.0392
Epigenome-wide DNA methylation in obsessive-compulsive disorder – a case-control study
Schiele Miriam, Germany

P.0397
Effect of anethole on spatial memory in rats on a high-calorie diet
Rafailova Elis, Bulgaria

P.0400
Perceived stress among patients with depression and anxiety in remission during the COVID-19 pandemic
Kamenova Ivayla, Bulgaria

P.0405
Immune-inflammation and structural neuroimaging differentiate bipolar and unipolar depression: a machine learning study
Colombo Federica, Italy

P.0412
Genetic dissection of the clinical heterogeneity of major depressive disorder
Oliva Vincenzo, Italy

P.0414
Pharmacogenetics of CYP2C19 in response and side effects to major depression treatment: a machine learning approach
Calabrò Marco, Italy

P.0415
A neurofunctional proxy of affect intensity provides unbiased support for the monoamine pathway
FreytagVirginie, Switzerland

P.0424
A multicentric multimodal in vivo microscopy MRI study of bipolar disorder reveals axonal loss and demyelination
Sarrazin, Samuel, France

P.0439
Evaluation of the relationship between neurocognitive characteristics and the tract of kynurenine in the offspring of bipolar disorder
Arıcı Sağlıyan, Gökçeçiçek, Türkiye

P.0440
Neurocognition across bipolar disorder phases in comparison with healthy control
Ciftci Elvan, Türkiye

P.0446
The safety and efficacy of COMP360 psilocybin therapy in treatment-resistant depression: results from a phase IIb randomised controlled trial
Hewitt Nilay, United Kingdom

P.0450
A phase 1/2 trial of a vaporized 5-Methoxy-N,N-Dimethyltryptamine formulation, in patients with treatment-resistant depression
Reckweg Johannes, The Netherlands

P.0458
Simvastatin and emotional processing: an experimental medicine study in healthy volunteers
Waters Shona, United Kingdom

P.0484
Investigation of the effects of carvacrol on cognitive functions in postmenopausal hypertensive rats
Ertas Busra, Türkiye

P.0554
Maternal stress affects human milk composition: a potential role in the transmission of maternal psychopathology to child development
Juncker Hannah, The Netherlands

P.0572
Flaxseed oil attenuates trimethyltin-induced neurodegeneration and gliosis in the hippocampus of female rats
Mitrović Nataša, Serbia

P.0573
Effect of complex neuroprotective therapy on functional recovery after stroke
Vorokhta Yurii, Ukraine

P.0575
Transdiagnostic individualised brain texture changes that are associated with symptom severity using contrast feature map
Korda Alexandra, Germany

P.0603
Immunohistochemical evidence that paroxetine discontinuation in mice is associated with increased activation of 5-HT neurons
Collins Helen, United Kingdom

P.0607
Manipulating a brain circuit associated with sociability by a two-recombinase system
Stoller Franziska, Germany

P.0619
Brain based BMIgap as a new tool to correlate obesity and neural alterations – a multicohort study
Khuntia Adyasha, Germany

P.0627
Mapping diagnostic trajectories from the first diagnosis of mental illness in the entire Danish population over two decades
Jørgensen Terese Sara Høj, Denmark

P.0643
Gray matter correlates of childhood maltreatment: investigation of robustness and replicability in a multi-cohort voxel-based analysis of 2952 adults
Goltermann Janik, Germany

P.0670
A human hippocampal transcriptomics-based drug screening approach identifies novel geroneuroprotective candidates
Rock Daniel, United Kingdom

P.0678
Food addiction in the overweight – the role of affective temperaments and eating behaviours
Jovic Jelena, Serbia

P.0724
The aftermath of COVID-19 lockdown – changing trends in eating disorders among children and adolescents in the psychiatry emergency department
Fortea Lydia, Spain

P.0730
Differential white matter involvement in drug-naïve children with obsessive-compulsive disorder and Tourette syndrome
Conte Giulia, Italy

P.0735
Association between CYP2C19 genotype and body weight with escitalopram exposure – a cross sectional study
Jeremic Aleksandra, Serbia

P.0737
Effects of personalized dosing based on drug plasma level quantification on effectiveness and safety of escitalopram treatment
Vuković Petar, Serbia

P.0746
Association between polygenic risk scores for psychiatric disorders and fluoxetine response in children and adolescent patients
Rodríguez Natalia, Spain

P.0749
Neutrophil/lymphocyte ratio is increased in elderly patients with first episode depression, but not in recurrent depression
Łucka Anna, Poland

P.0750
The effect of transcutaneous vagus nerve stimulation on interleukin 6 and c-reactive protein during stress in depression
Schiweck Carmen, Germany

P.0751
Different relationship of neurological and non-neurological conditions with non-suicidal self-injury among youth with emotional disorders
Lero Marija, Serbia

P.0767
Dynamics of depressive disorders in children and adolescents during COVID-19 pandemic
Andrei Lucia Emanuela, Romania

P.0777
Initiation of antidepressant treatment and the risk of manic episodes in pediatric unipolar depression
Virtanen Suvi, Sweden

P.0792
Pregnancy and postpartum period associated severe mental disorders in a hospital-based cohort
Büyüktopcu Emiralp, Türkiye

P.0805
Age-dependent analysis of the pro- and anti-inflammatory factors gene expression in the brain of the genetically modified knock-in mice APPNL-F/NL-F
Tylek Kinga, Poland

P.0809
Single, conditional, lentiviral CRISPR/Cas9 vectors for efficient mutagenesis in neurons – a possible new strategy for modeling prodromal Parkinson’s disease
Barut Justyna, Poland

P.0819
CPL500036 – a novel inhibitor of phosphodiesterase 10A – attenuates the development of L-DOPA-induced dyskinesias in 6-OHDA lesioned rats
Matłoka Mikołaj, Poland

P.0831
Altered volumes of the amygdala and hippocampus in the suicidal brain of patients with first episode psychosis
Sen Meltem, Türkiye

P.0876
Reduced amygdala volume mediates the association between developmental trauma and psychotic experiences in adulthood – findings from a population-based cohort
Jung Paul Gu-Yun, United Kingdom

P.0882
Salivary cortisol levels in relation to depression and anxiety symptoms in healthy volunteers following a chronic stress period
Kolcsar Melinda, Romania

P.0890
Evaluation of modulatory effect of β1-adrenergic receptor blockade during chronic restraint stress on glutamate transmission in frontal cortex of rats
Zelek-Molik Agnieszka, Poland

P.0908
Intrinsic causal network dynamics of emotion regulation tendency – high and low reappraisal tendency reflected in resting-state fMRI data
Hajrić, Mirna, Austria

P.0909
Multivariate relationships among social stressors and functional brain connectivity – a transdiagnostic dimensional approach
Maggioni Eleonora, Italy

P.0949
Repetitive stimulation of lateral and/or perifornical hypothalamus elevates CSF orexin-A, shortens coma time; accelerates wakefulness and sleep recoveries in rats
Bejanishvili Khatuna, Georgia

P.0956
From neurogenesis to immune response: how neural stem cells switch fate to communicate with immune cells
Nissen Tinne, United Kingdom

P.0965
Differences in patterns of stimulant use and their impact on first-episode psychosis incidence – an analysis of the EUGEI study
Rodríguez-Toscano Elisa, Spain