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Meetings
During the year, the Pharmacogenomics and Transcriptomics Network organises meetings for its members (also at the annual ECNP Congress).

Summer school in precision psychiatry: Clinical, -omics and imaging biomarkers of complex psychiatric disorders

  • When: 28-30 April 2025

  • About
    Psychiatric disorders and suicidal behaviour are the result of complex interactions between genomic variations, epigenetic modifications, and other regulatory mechanisms that affect gene expression. Understanding the mechanisms underlying gene expression may not only help in diagnosis and prediction of treatment response but also provide valuable insights into the molecular mechanisms of drug’s action. Using, for example, co-expression network analysis-based methods, disease-relevant clusters of co-regulated genes can be identified and further integrated with genetic and epigenetic data for a comprehensive investigation of biological underpinnings of mental illness and for predicting psychiatric disorders and suicide risk.

    This summer school will focus on the integration of clinical, imaging, and genetics/omics biomarkers to diagnose and improve pharmacological treatment of psychiatric disorders and related conditions including suicidal behaviours. It aims to blend clinical psychiatry with molecular genetics and transcriptomics through theoretical sessions and practical workshops, data management, analysis, and interpretation for psychiatric conditions and traits, including major depression, bipolar disorder, schizophrenia, and suicidality.

  • How to register
    For more information on how to register, please see the flyer and visit the website.

This school is organised by the ECNP Network on Pharmacogenomics and Transcriptomics and the ECNP Network on Suicide Research and Prevention

Research projects

  • PSYCH STRATA — A Stratified Treatment Algorithm in Psychiatry: a programme on stratified pharmacogenomics in severe mental illness (HORIZON HLTH 2021 STAYHLTH 01)
  • PROMPT – Toward PrecisiOn Medicine for the Prediction of Treatment response in major depressive disorder through stratification of combined clinical and -omics signatures (EraPerMed Grant)

Recommended publications

Authors  Year
Title
Journal and link to the article
Minelli et al.  
2022 Evaluating study designs and treatment outcomes of antidepressant pharmacogenetic clinical trials — challenges and future perspectives. A critical review.
European Neuropsychopharmacology
Pisanu et al.
2022 Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review. 
European Neuropsychopharmacology
Fanelli et al.
2022  A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response
European Neuropsychopharmacology
Xicota et al.
2022 Recommendations for pharmacotranscriptomic profiling of drug response in CNS disorders
European Neuropsychopharmacology